SCHEMBL2200643

SCHEMBL2200643

COc1c(B(O)O)ccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ERN1 O75460 1/20 0.46
MAPT P10636 1/20 0.46
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
ENPP2 Q13822 1/20 0.44
POLB P06746 2/20 0.42
CYP2A6 P11509 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RAB9A P51151 2/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955621 1.00 HPGD (0.49) HPGDALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL2323373 0.80 SLC2A1 (0.47) ALDH1A1KDM4ETSHRHSD17B10RAB9A
SCHEMBL29952787 0.79 ERN1 (0.36) HPGDALDH1A1KDM4EERN1MAPT
SCHEMBL29951035 0.79 HTT (0.47) HPGDALDH1A1ERN1MAPTCYP1A1
SCHEMBL1824124 0.78 TSHR (0.56) HPGDALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL19082467 0.77 MAPT (0.41) HPGDALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL19097521 0.77 SLC2A1 (0.46) KDM4EENPP2CYP2A6
SCHEMBL19110418 0.77 KDM4E (0.41) HPGDALDH1A1KDM4EERN1MAPT
Boric Acid SCHEMBL28424228 0.76 ERN1 (0.57) HPGDALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL3818138 0.76 ESR1 (0.54) HPGDALDH1A1KDM4EMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333000-B Organometallic compound and organic light emitting diode including the same 乐金显示有限公司 2025-05-06 CN disclosed
US-20240237516-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LT MATERIALS CO., LTD. (KR) 2024-07-11 US disclosed
CN-117279918-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-12-22 CN disclosed
CN-116964060-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-10-27 CN disclosed
EP-4265617-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-10-25 EP disclosed
CN-116333000-A Organometallic compound and organic light emitting diode including the same 乐金显示有限公司 2023-06-27 CN disclosed
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
WO-2023085834-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed
US-20230090185-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DIODE LT MATERIALS CO., LTD. (KR) 2023-03-23 US disclosed
WO-2023287252-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-01-19 WO disclosed
EP-1868998-A2 NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS Insa Rouen (FR) 2007-12-26 EP disclosed
EP-1731507-A1 New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents Institut National des Sciences Appliquees de Rouen (INSA) (FR) 2006-12-13 EP disclosed
WO-2006103120-A2 NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS INSA ROUEN (FR) 2006-10-05 WO disclosed
EP-1670768-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2006-06-21 EP disclosed
EP-1349836-B1 TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS LILLY CO ELI (US) 2006-06-14 EP disclosed
US-6992100-B2 sPLA2 inhibitors ELI LILLY AND COMPANY (US) 2006-01-31 US disclosed
WO-2005037796-A1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA ELI LILLY AND COMPANY (US) 2005-04-28 WO disclosed
US-20040092543-A1 Novel spla2 inhibitors BEIGHT DOUGLAS WADE (US) 2004-05-13 US disclosed
EP-1349836-A2 TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 2003-10-08 EP disclosed
WO-2002050029-A2 TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 2002-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230090185-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DIODE ORC3, ODC1, CRY1 HPGD 1016/4885ALDH1A1 262/4885KDM4E 2383/4885
US-20040092543-A1 Novel spla2 inhibitors PLA2G12A, PLAAT2, SPINT2 HPGD 802/4885ALDH1A1 3868/4885KDM4E 4380/4885
US-20240237516-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, CRY1, CRY2 HPGD 2531/4885ALDH1A1 269/4885KDM4E 3822/4885
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME CRY1, ZFX, PPOX HPGD 1087/4885ALDH1A1 315/4885KDM4E 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.