Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28767146 | 0.91 | ERN1 (0.54) | ESR1ESR2PTPN22ALDH1A1POLB | |
| SCHEMBL11504661 | 0.90 | HPRT1 (0.52) | ESR1ESR2PTPN22ALDH1A1KDM4E | |
| SCHEMBL15476424 | 0.86 | ALDH1A1 (0.50) | ESR1ESR2PTPN22ALDH1A1KDM4E | |
| SCHEMBL10236585 | 0.84 | PTPN22 (0.50) | PTPN22ALDH1A1KDM4EPOLBERN1 | |
| SCHEMBL70005 | 0.83 | PTPN22 (0.58) | PTPN22ALDH1A1KDM4EPOLBERN1 | |
| SCHEMBL12486732 | 0.82 | ESR1 (0.54) | ESR1ESR2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL31570914 | 0.82 | ESR1 (0.54) | ESR1ESR2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL28372416 | 0.80 | CYP1A2 (0.44) | PTPN22ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL7595465 | 0.79 | ALOX5 (0.54) | PTPN22ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL16082559 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701608-B2 | Process for the synthesis of 7-methoxy-naphthalene-1-carbaldehyde and application in the synthesis of agomelatine | LES LABORATORIES SERVIER (FR) | 2017-07-11 | — | — | US | claimed |
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | LES LABORATOIRES SERVIER (FR) | 2016-10-20 | — | — | US | claimed |
| US-5182213-A | Coupling a Phenylenediamine and a Naphthol | MILES INC. (US) | 1993-01-26 | — | — | US | claimed |
| EP-0504663-A1 | Peroxidase indicator system for basic media | Bayer Corporation (US) | 1992-09-23 | — | — | EP | claimed |
| US-4533766-A | Process for the production of dihydroxybenzenes | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | claimed |
| CN-112088198-B | Treatment agent for 6-valent chromium, method for treating pollutant containing 6-valent chromium, and method for treating bone ash containing 6-valent chromium | 西铁城时计株式会社 | 2023-10-03 | — | — | CN | disclosed |
| CN-106536518-B | Anthelmintic compounds | 勃林格殷格翰动物保健美国公司 | 2020-05-12 | — | — | CN | disclosed |
| US-7553963-B2 | Liquid partially trimerized and allophanized polyisocyanates based on toluene diisocyanate and diphenylmethane diisocyanate | BAYER MATERIALSCIENCE LLC (US) | 2009-06-30 | — | — | US | disclosed |
| EP-1715839-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1682595-A1 | LIQUID PARTIALLY TRIMERIZED AND ALLOPHANIZED POLYISOCYANATES BASED ON TOLUENE DIISOCYANATE AND DIPHENYLMETHANE DIISOCYANATE | Bayer MaterialScience LLC (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005063178-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005044886-A1 | LIQUID PARTIALLY TRIMERIZED AND ALLOPHANIZED POLYISOCYANATES BASED ON TOLUENE DIISOCYANATE AND DIPHENYLMETHANE DIISOCYANATE | BAYER MATERIALSCIENCE LLC (US) | 2005-05-19 | — | — | WO | disclosed |
| US-20050096449-A1 | Liquid partially trimerized and allophanized polyisocyanates based on toluene diisocyanate and diphenylmethane diisocyanate | BAYER MATERIALSCIENCE LLC | 2005-05-05 | — | — | US | disclosed |
| US-6127308-A | Trimer catalyst system for aliphatic and aromatic isocyanates | BAYER CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-6063891-A | PREPOLYMER OF ALLOPHANATE-MODIFIED, PARTIALLY TRIMERIZED TOLUENE DIISOCYANATE AND ISOCYANATE-REACTIVE POLYOL | BAYER CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |
| US-6028158-A | Freeze-stable allophanate-modified toluene diisocyanate trimers | BAYER CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-5955609-A | Trimer catalyst system for aliphatic and aromatic isocyanates | BAYER CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| US-5864406-A | Method and apparatus for forming halftone images on organic-silver-salt-based printing plates | CANON KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5182213-A | Coupling a Phenylenediamine and a Naphthol | MILES INC. (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0504663-A1 | Peroxidase indicator system for basic media | Bayer Corporation (US) | 1992-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | COMT, TPH1, TPH2 | ESR1 4184/4885ESR2 3921/4885PTPN22 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.