SCHEMBL22007580

SCHEMBL22007580

c1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccc(-c6ccc(-n7nc8ccccc8n7)cc6)cc5)cc4)cc3)cc2)c2ccc(-c3ccc(-n4nc5ccccc5n4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.59
HPGD P15428 4/20 0.59
HTT P42858 1/20 0.47
ALDH1A1 P00352 8/20 0.42
MAPT P10636 6/20 0.42
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
STAT1 P42224 1/20 0.42
ALOX5 P09917 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
APP P05067 2/20 0.39
SMN1; SMN2 Q16637 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22007450 1.00 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL20656694 1.00 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22688044 1.00 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22008503 1.00 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL20656693 1.00 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22688038 0.98 KDM4E (0.57) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22007581 0.98 KDM4E (0.57) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL26221520 0.98 KDM4E (0.57) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22686571 0.96 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT
SCHEMBL22653489 0.96 KDM4E (0.59) KDM4EHPGDHTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME SFC CO., LTD. (KR) 2023-09-07 US disclosed
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME SFC CO., LTD. (KR) 2023-09-07 US disclosed
US-20220149291-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2022-05-12 US disclosed
US-20220102635-A1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND SFC CO., LTD. (KR) 2022-03-31 US disclosed
US-11056653-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-07-06 US disclosed
US-20210167293-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2021-06-03 US disclosed
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same SFC CO., LTD. (KR) 2021-04-20 US disclosed
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2020-12-17 US disclosed
US-20200328353-A1 Organic Electroluminescence Device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-10-15 US disclosed
WO-2020137724-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2020-07-02 WO disclosed
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2020-06-04 US disclosed
US-20200161552-A1 INDOLOCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885HTT 664/4885
US-20220102635-A1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND TRPA1, TYR, ZKSCAN2 KDM4E 582/4885HPGD 3907/4885HTT 2112/4885
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME ARNT, AHR, TYR KDM4E 812/4885HPGD 2734/4885HTT 548/4885
US-20210167293-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885HTT 664/4885
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885HTT 664/4885
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, AP2A2, CCNA1 KDM4E 3986/4885HPGD 3352/4885HTT 3852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.