Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.60 |
| ▸ | FAAH | O00519 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15606248 | 0.92 | PTGS1 (0.70) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL1965501 | 0.81 | MGLL (0.62) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL155346 | 0.81 | PTGS1 (0.85) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL1704532 | 0.81 | MGLL (0.62) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL3047985 | 0.79 | PTGS1 (0.81) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL3049679 | 0.79 | PTGS1 (0.81) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL6473262 | 0.79 | PTGS1 (0.81) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17924135 | 0.79 | PTGS1 (0.81) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10014802 | 0.79 | MGLL (0.60) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL16539081 | 0.79 | MGLL (0.60) | MGLLFAAHPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185803-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-06-16 | — | — | US | disclosed |
| US-20220177461-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220016277-A1 | MACROCYCLIC COMPLEXES OF RADIONUCLIDES AND THEIR USE IN RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-01-20 | — | — | US | disclosed |
| US-20200157087-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185803-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | MGLL 3046/4885FAAH 4785/4885PTGS1 4742/4885 |
| US-20200157087-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | MGLL 3046/4885FAAH 4785/4885PTGS1 4742/4885 |
| US-20220016277-A1 | MACROCYCLIC COMPLEXES OF RADIONUCLIDES AND THEIR USE IN RADIOTHERAPY OF CANCER | PSMA1, KLK3, FOLH1 | MGLL 2768/4885FAAH 4731/4885PTGS1 4611/4885 |
| US-20220177461-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | MGLL 3046/4885FAAH 4785/4885PTGS1 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.