Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 9/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740559 | 0.76 | ESR1 (0.52) | CYP3A4IDO1 | |
| SCHEMBL28591555 | 0.74 | TRPA1 (0.43) | — | |
| SCHEMBL3568612 | 0.74 | IDO1 (0.46) | IDO1 | |
| SCHEMBL28386811 | 0.74 | IDO1 (0.46) | IDO1 | |
| SCHEMBL19692606 | 0.74 | ALDH1A1 (0.50) | CYP3A4 | |
| SCHEMBL1822656 | 0.74 | F11 (0.56) | — | |
| SCHEMBL1358563 | 0.74 | IDO1 (0.46) | IDO1 | |
| SCHEMBL15106880 | 0.74 | CA1 (0.46) | IDO1 | |
| SCHEMBL19956177 | 0.73 | APP (0.31) | APP | |
| SCHEMBL219668 | 0.72 | CA1 (0.56) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11061169-B2 | Contact lens with phosphorylcholine-modified polyvinylalcohols therein | ALCON INC. (CH) | 2021-07-13 | — | — | US | disclosed |
| US-20210077385-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | ALCON INC. (CH) | 2021-03-18 | — | — | US | disclosed |
| US-20200158913-A1 | CONTACT LENS WITH PHOSPHORYLCHOLINE-MODIFIED POLYVINYLALCOHOLS THEREIN | ALCON INC. (CH) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077385-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | BRI3BP, BRWD1, HRH2 | CYP3A4 291/4885IDO1 969/4885APP 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.