SCHEMBL22011025

SCHEMBL22011025

Cc1oc2c(Br)cc(Cc3cc4cccc(Br)c4o3)cc2c1C=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.35
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21964009 0.75 LOXL2 (0.39) LOXL2MAOAMAOB
SCHEMBL1851853 0.70 PNMT (0.40) LOXL2
SCHEMBL1850517 0.69 LOXL2 (0.35) LOXL2MAOAMAOB
SCHEMBL3211830 0.69 GRM2 (0.37) LOXL2MAOB
SCHEMBL1856108 0.69 CNR2 (0.46) MAOB
SCHEMBL16795603 0.68 LOXL2 (0.41) LOXL2MAOAMAOB
SCHEMBL24923783 0.68 CYP11B1 (0.40) LOXL2
SCHEMBL1847848 0.66 GPR52 (0.51) MAOB
SCHEMBL3883498 0.66 MAOB (0.41) LOXL2MAOAMAOB
SCHEMBL3220518 0.65 CA2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099341-A1 ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF DEBIOPHARM INTERNATIONAL S.A. (CH) 2020-05-22 WO disclosed