Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.45 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PYGB | P11216 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358699 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL10147764 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL10147767 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL25140767 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL19430676 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL23591372 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL264028 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL23266122 | 0.98 | L3MBTL1 (0.49) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL20713594 | 0.98 | L3MBTL1 (0.49) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL24825613 | 0.98 | L3MBTL1 (0.49) | L3MBTL1LGALS1LGALS3LGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660911-B2 | Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660911-B2 | Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria | ATP5ME, ATP6V1E1, ATF4 | L3MBTL1 3231/4885LGALS1 3884/4885LGALS3 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.