SCHEMBL23266122

SCHEMBL23266122

CC(C)(C)C1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ LGALS1 P09382 2/20 0.48
▸ LGALS3 P17931 2/20 0.48
▸ LGALS9 O00182 1/20 0.48
▸ LGALS8 O00214 1/20 0.48
▸ MAPT P10636 1/20 0.47
▸ PYGB P11216 7/20 0.42
▸ GAA P10253 1/20 0.42
▸ POLB P06746 1/20 0.39
▸ CA12 O43570 3/20 0.39
▸ CA1 P00915 3/20 0.39
▸ CA2 P00918 3/20 0.39
▸ CA9 Q16790 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14556020 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL14106729 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL21539004 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL22697521 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL24825613 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL10038938 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL24824212 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL24824209 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL20713594 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL18158169 1.00 L3MBTL1 (0.49) L3MBTL1LGALS1LGALS3LGALS9LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018182-A1 GLUCOCORTICOID RECEPTOR AGONISTS ELI LILLY AND COMPANY 2024-01-18 — — US disclosed
US-11787834-B2 Glucocorticoid receptor agonists ELI LILLY AND COMPANY (US) 2023-10-17 — — US disclosed
US-20230193336-A1 ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 — — US disclosed
US-20230193336-A1 ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 — — US disclosed
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 — — US disclosed
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 — — US disclosed
US-20230124589-A1 Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis DOUBLERAINBOW BIOSCIENCES INC. 2023-04-20 — — US disclosed
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2022-05-10 — — US disclosed
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2021-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018182-A1 GLUCOCORTICOID RECEPTOR AGONISTS NR3C1, NR3C2, MC2R L3MBTL1 3775/4885LGALS1 2960/4885LGALS3 2007/4885
US-11787834-B2 Glucocorticoid receptor agonists NR3C1, NR3C2, MC2R L3MBTL1 3775/4885LGALS1 2960/4885LGALS3 2007/4885
US-20230124589-A1 Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis UGGT1, UGDH, GALE L3MBTL1 1359/4885LGALS1 402/4885LGALS3 383/4885
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate VEGFA, FLT4, FLT1 L3MBTL1 4302/4885LGALS1 846/4885LGALS3 509/4885
US-20230193336-A1 ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION UGDH, IDH1, G6PD L3MBTL1 1574/4885LGALS1 435/4885LGALS3 493/4885
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug GALE, UGGT1, DERA L3MBTL1 1063/4885LGALS1 396/4885LGALS3 346/4885
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE VEGFA, FLT4, FLT1 L3MBTL1 4302/4885LGALS1 846/4885LGALS3 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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