SCHEMBL22011130

SCHEMBL22011130

CCCOc1ccc(-c2ccc(-c3cc4oc5cc(CCc6ccc(CCC)cc6)c(F)c(F)c5c4c(F)c3F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.41
MAOA P21397 3/20 0.40
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ACACB O00763 2/20 0.35
ACACA Q13085 2/20 0.35
C3AR1 Q16581 1/20 0.35
ALOX5 P09917 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SLC5A1 P13866 1/20 0.33
SLC5A2 P31639 1/20 0.33
ALPL P05186 1/20 0.32
HTR1A P08908 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011081 0.82 MAOB (0.36) MAOBMAOAC3AR1ALOX5ALDH1A1
SCHEMBL22011138 0.79 MAPT (0.37) L3MBTL1ALOX5SMN1; SMN2MAPTNPC1
SCHEMBL9563718 0.79 ALDH1A1 (0.48) LMNAL3MBTL1ACACBACACAC3AR1
SCHEMBL22011103 0.78 RARB (0.42) LMNASMN1; SMN2MAPTALDH1A1RAB9A
SCHEMBL22011820 0.78 RARB (0.46) HSD17B10
SCHEMBL9493822 0.77 LMNA (0.49) LMNAL3MBTL1ACACBC3AR1SMN1; SMN2
SCHEMBL22011220 0.76 RARB (0.33)
SCHEMBL9664301 0.75 RARB (0.47) MAOBLMNAL3MBTL1ACACBACACA
SCHEMBL22010983 0.75 ALDH1A1 (0.38) LMNASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL9563775 0.74 CYP3A4 (0.49) LMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 MAOB 787/4885MAOA 1418/4885LMNA 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.