SCHEMBL22011138

SCHEMBL22011138

CCCc1ccc(-c2ccc(-c3cc4oc5cc(-c6ccc(CC)cc6)c(F)c(F)c5c4c(F)c3F)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
QPCT Q16769 1/20 0.36
MCL1 Q07820 1/20 0.35
RARB P10826 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GCGR P47871 1/20 0.33
MAPK14 Q16539 1/20 0.33
ALOX5 P09917 1/20 0.33
GFER P55789 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011221 0.83 SPHK1 (0.34) MAPTQPCT
SCHEMBL22011081 0.82 MAOB (0.36) ALOX5ABCB1
SCHEMBL9563769 0.81 TAAR1 (0.41) MAPTMCL1RARBNPC1RAB9A
SCHEMBL22011103 0.80 RARB (0.42) MAPTRARBRAB9AMAPK14RARA
SCHEMBL9493621 0.80 TAAR1 (0.42) MAPTMCL1RARBNPC1RAB9A
SCHEMBL22011130 0.79 MAOB (0.41) MAPTNPC1RAB9AALOX5SMN1; SMN2
SCHEMBL22010835 0.77 RARB (0.40) MAPTRARBRAB9ARARARARG
SCHEMBL9563689 0.76 MCL1 (0.41) MAPTMCL1RARBNPC1RAB9A
SCHEMBL22010955 0.76 RARB (0.40) MAPTRARBRAB9ARARARARG
SCHEMBL22011820 0.76 RARB (0.46) RARBRARARARGHSD17B10MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 MAPT 1234/4885QPCT 2447/4885MCL1 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.