SCHEMBL22011803

SCHEMBL22011803

CCCCc1ccc2cc(-c3cc4oc5cc(OCC)c(F)c(F)c5c4c(F)c3F)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 2/20 0.35
S1PR1 P21453 3/20 0.34
FGFR1 P11362 1/20 0.34
FGFR2 P21802 1/20 0.34
CYP2C8 P10632 1/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MPL P40238 3/20 0.33
S1PR3 Q99500 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22010955 0.86 RARB (0.40) S1PR1MAPTRAB9AL3MBTL1S1PR3
SCHEMBL22010835 0.85 RARB (0.40) MAPTRAB9AL3MBTL1MPLFFAR4
SCHEMBL22010998 0.84 RARB (0.44) S1PR1MAPTRAB9AL3MBTL1MPL
SCHEMBL22010988 0.83 MPL (0.37) S1PR1FGFR1FGFR2MAPTRAB9A
SCHEMBL22010820 0.83 RARB (0.40) S1PR1MPL
SCHEMBL22011189 0.80 RARB (0.37) CALM1S1PR1MAPTRAB9AL3MBTL1
SCHEMBL22011104 0.79 NAAA (0.33) MAPTRAB9AL3MBTL1TP53
SCHEMBL22011081 0.76 MAOB (0.36) S1PR1CA9FFAR4GABRA1GABRB2
SCHEMBL16772341 0.76 MPL (0.40) S1PR1FGFR1FGFR2MAPTRAB9A
SCHEMBL20102448 0.75 FGFR2 (0.38) CALM1FGFR1FGFR2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 CALM1 2793/4885S1PR1 1710/4885FGFR1 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.