SCHEMBL22011104

SCHEMBL22011104

CCCCCc1ccc(-c2cc3oc4cc(OCC)c(F)c(F)c4c3c(F)c2F)cc1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.33
TSHR P16473 2/20 0.33
FPR1 P21462 2/20 0.32
MAPT P10636 4/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALOX5 P09917 7/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TYR P14679 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAOB P27338 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011818 0.86 MAOB (0.35) NAAAMAOBRARBRARARARG
SCHEMBL22011802 0.85 CTSL (0.38) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL22010955 0.85 RARB (0.40) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL22010835 0.84 RARB (0.40) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL22010998 0.83 RARB (0.44) MAPTALDH1A1RAB9AL3MBTL1TP53
SCHEMBL22010811 0.82 KDM4E (0.36) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL22011813 0.81 S1PR1 (0.35) MAPTRAB9AL3MBTL1ALOX5THRB
SCHEMBL22011803 0.79 CALM1 (0.35) MAPTRAB9AL3MBTL1TP53
SCHEMBL22010964 0.78 KDM4E (0.37) TSHRMAPTMEN1KMT2AALDH1A1
SCHEMBL424417 0.78 NAAA (0.40) NAAATSHRMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 NAAA 4469/4885TSHR 3279/4885FPR1 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.