Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635526 | 0.82 | CA2 (1.00) | CA2GAASMN1; SMN2CA1CA12 | |
| SCHEMBL24129426 | 0.80 | CA2 (0.59) | CA2GAAUCHL1SMN1; SMN2PSIP1 | |
| SCHEMBL23554860 | 0.80 | CA2 (0.59) | CA2GAAUCHL1SMN1; SMN2PSIP1 | |
| SCHEMBL12309787 | 0.78 | CA2 (0.69) | CA2GAAUCHL1SMN1; SMN2PSIP1 | |
| SCHEMBL20698828 | 0.78 | HRH3 (0.48) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL20692306 | 0.78 | ALDH1A1 (0.54) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL6038843 | 0.77 | CA2 (0.61) | CA2UCHL1SMN1; SMN2PSIP1KMT2A | |
| SCHEMBL23512338 | 0.77 | CA2 (0.88) | CA2GAAUCHL1SMN1; SMN2CA1 | |
| SCHEMBL678812 | 0.77 | CA2 (0.67) | CA2GAAUCHL1PSIP1KMT2A | |
| SCHEMBL24129791 | 0.76 | CA2 (0.55) | CA2GAAUCHL1SMN1; SMN2PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220402-A1 | ENPP1 MODULATORS AND PRODUCTS AND USES THEREOF | GOSSAMER BIO SERVICES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-16 | — | — | US | disclosed |
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | CA2 1210/4885GAA 1470/4885UCHL1 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.