Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942933 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAMAPTTP53CYP1A2 | |
| SCHEMBL9631626 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL9996097 | 0.73 | MAPK1 (0.34) | LMNAMAPTTP53CYP1A2CYP3A4 | |
| SCHEMBL5029369 | 0.72 | PDE4B (0.36) | SMN1; SMN2LMNAMAPTTP53CYP1A2 | |
| SCHEMBL17163859 | 0.69 | CFTR (0.41) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL5027310 | 0.68 | CRHBP (0.37) | SMN1; SMN2LMNAMAPTTP53CYP1A2 | |
| SCHEMBL1306039 | 0.67 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNACYP1A2CYP3A4EDNRA | |
| SCHEMBL146501 | 0.67 | LMNA (0.41) | LMNAMAPTTP53CYP1A2CYP3A4 | |
| SCHEMBL18691989 | 0.67 | LMNA (0.41) | LMNAMAPTTP53CYP1A2CYP3A4 | |
| SCHEMBL13824907 | 0.67 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPTMAPK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102126-A1 | IRON-CATALYZED SELECTIVE PRODUCTION OF METHYL ESTERS FROM ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2020-05-22 | — | — | WO | disclosed |