Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874524 | 0.86 | ITGB3 (0.64) | ALOX15ALDH1A1SMN1; SMN2PTPN7MEN1 | |
| SCHEMBL31370125 | 0.86 | ITGB3 (0.64) | ALOX15ALDH1A1SMN1; SMN2PTPN7MEN1 | |
| SCHEMBL9651945 | 0.86 | SLC6A4 (0.56) | ALOX15ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL1874526 | 0.86 | ITGB3 (0.64) | ALOX15ALDH1A1SMN1; SMN2PTPN7MEN1 | |
| SCHEMBL14944934 | 0.86 | SLC6A4 (0.56) | ALOX15ALDH1A1TSHRSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9765308 | 0.85 | SLC6A4 (0.54) | ALOX15ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL26168286 | 0.85 | ALDH1A1 (0.51) | ALOX15ALDH1A1TSHRSMN1; SMN2FFAR1 | |
| SCHEMBL10884785 | 0.83 | ITGB3 (0.50) | ALOX15ALDH1A1TSHRSMN1; SMN2FFAR1 | |
| SCHEMBL10884788 | 0.83 | ITGB3 (0.50) | ALOX15ALDH1A1TSHRSMN1; SMN2FFAR1 | |
| SCHEMBL16549810 | 0.83 | ALOX15 (0.49) | ALOX15ALDH1A1TSHRSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099596-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | UNIVERSITE DE ROUEN NORMANDIE (FR) | 2020-05-22 | — | — | WO | disclosed |