Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18737541 | 0.99 | RXRA (0.35) | RXRARXRBRXRGALDH1A1ZDHHC20 | |
| SCHEMBL18743181 | 0.91 | RXRA (0.30) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL21166373 | 0.88 | RXRA (0.34) | RXRARXRBRXRGZDHHC20 | |
| SCHEMBL22038993 | 0.88 | RXRA (0.32) | RXRARXRBRXRG | |
| SCHEMBL18999618 | 0.87 | RXRA (0.34) | RXRARXRBRXRGZDHHC20 | |
| SCHEMBL18737544 | 0.87 | RXRA (0.34) | RXRARXRBRXRGZDHHC20 | |
| SCHEMBL24690710 | 0.85 | ALDH1A1 (0.32) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL24690402 | 0.84 | ZDHHC20 (0.42) | ALDH1A1ZDHHC20 | |
| SCHEMBL18896626 | 0.84 | RXRA (0.31) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL18431665 | 0.84 | RXRA (0.31) | RXRARXRBRXRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662195-B2 | Protein kinase conjugates and inhibitors | CELGENE CAR LLC (BM) | 2020-05-26 | — | — | US | disclosed |
| US-20170174691-A1 | Protein Kinase Conjugates and Inhibitors | CELGENE CAR LLC (BM) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174691-A1 | Protein Kinase Conjugates and Inhibitors | MAP3K20, ADK, TTK | RXRA 4248/4885RXRB 4309/4885RXRG 4253/4885 |
| US-10662195-B2 | Protein kinase conjugates and inhibitors | MAP3K20, ADK, TTK | RXRA 4248/4885RXRB 4309/4885RXRG 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.