SCHEMBL22014111

SCHEMBL22014111

Oc1cc(S)cc(O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 2/20 0.47
SELP P16109 2/20 0.47
SELE P16581 1/20 0.47
LMNA P02545 5/20 0.41
TDP1 Q9NUW8 5/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
MAPT P10636 3/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA6 P23280 2/20 0.41
FUT7 Q11130 2/20 0.41
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CA12 O43570 1/20 0.41
CA3 P07451 1/20 0.41
FUT4 P22083 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21767287 0.74 GABRA1 (0.59) LMNAALDH1A1HPGDCA1CA2
SCHEMBL18377357 0.73 TRPV4 (0.46) CA1CA6CA12CA3CA5A
SCHEMBL19909819 0.72 HSD17B10 (0.39) LMNATDP1ALDH1A1HPGDHSD17B10
SCHEMBL10826782 0.71 SELL (0.40) SELLSELPSELELMNATDP1
SCHEMBL3801540 0.71
SCHEMBL17520402 0.71 SELL (0.47) SELLSELPSELELMNATDP1
SCHEMBL10826108 0.71
SCHEMBL25183526 0.69 SELL (0.53) SELLSELPSELELMNATDP1
SCHEMBL67497 0.69 BACE1 (0.54) SELLSELPSELELMNATDP1
SCHEMBL63242 0.67 ACHE (0.43) SELLSELPSELECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020098630-A1 ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) 2020-05-22 WO disclosed