Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785011 | 0.82 | GCGR (0.33) | GCGRGABRA1GABRG2GABRB3 | |
| SCHEMBL22010373 | 0.81 | — | — | |
| SCHEMBL28799188 | 0.80 | GABRA1 (0.47) | GABRA1POLB | |
| SCHEMBL9804429 | 0.80 | CA1 (0.35) | GABRA1GABRG2GABRB3 | |
| SCHEMBL24783786 | 0.80 | GCGR (0.32) | GCGRGABRA1GABRG2GABRB3 | |
| SCHEMBL24784393 | 0.77 | GABRA1 (0.33) | GABRA1GABRG2GABRB3 | |
| SCHEMBL25138979 | 0.76 | KDM4E (0.34) | — | |
| SCHEMBL8125391 | 0.75 | GABRA1 (0.54) | GABRA1GABRG2GABRB3 | |
| SCHEMBL25138922 | 0.74 | GCGR (0.38) | GCGRGABRA1GABRG2GABRB3 | |
| SCHEMBL19508138 | 0.71 | NLRP3 (0.36) | GCGRGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |