Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799188 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2GABRB1 | |
| SCHEMBL22014427 | 0.80 | GCGR (0.32) | GABRA1GABRG2GABRB3 | |
| SCHEMBL9028340 | 0.78 | LMNA (0.43) | CA1CA2XDHGABRA1GABRB2 | |
| SCHEMBL22010373 | 0.77 | — | — | |
| SCHEMBL25138979 | 0.76 | KDM4E (0.34) | ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8125391 | 0.75 | GABRA1 (0.54) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL27776893 | 0.74 | CA1 (0.39) | CA1CA2XDHGABRA1GABRB2 | |
| SCHEMBL24784393 | 0.73 | GABRA1 (0.33) | GABRA1GABRG2GABRB3 | |
| SCHEMBL28938963 | 0.72 | CYP3A4 (0.41) | XDHGABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL5598779 | 0.72 | GSR (0.53) | CA1CA2XDHGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186255-B1 | PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS | ETHYL CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0186255-A2 | Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols | ETHYL CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |