Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014606 | 0.86 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL22015230 | 0.84 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KDM4EHDAC1HSD17B10 | |
| SCHEMBL22015899 | 0.83 | NPC1 (0.36) | ALDH1A1SMN1; SMN2NPC1ADRB2RAB9A | |
| SCHEMBL21963673 | 0.81 | — | — | |
| SCHEMBL22014610 | 0.79 | CYP3A4 (0.35) | ALDH1A1SMN1; SMN2KMT2ARPS6KB2LMNA | |
| Trifluoroacetic Acid SCHEMBL21963677 | 0.78 | CYP1A2 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL22014609 | 0.77 | — | — | |
| SCHEMBL22014602 | 0.76 | HDAC1 (0.31) | HDAC1 | |
| Hydrochloric Acid SCHEMBL21963932 | 0.74 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL22015232 | 0.74 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099407-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |