Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015234 | 0.83 | ALDH1A1 (0.39) | NPC1RAB9AADRB2LMNAPKM | |
| SCHEMBL22014610 | 0.78 | CYP3A4 (0.35) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22020526 | 0.69 | HDAC4 (0.34) | NPC1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22014606 | 0.69 | ALDH1A1 (0.38) | RAB9ALMNAPKMALDH1A1USP2 | |
| SCHEMBL21431477 | 0.68 | LTA4H (0.40) | NPC1RAB9AADRB2LMNAECE1 | |
| SCHEMBL22015230 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2GAATSHR | |
| SCHEMBL21963673 | 0.65 | — | — | |
| SCHEMBL291399 | 0.64 | ALDH1A1 (0.44) | NPC1RAB9ALMNAPKMALDH1A1 | |
| SCHEMBL6248862 | 0.64 | LMNA (0.63) | NPC1RAB9AADRB2LMNAPKM | |
| SCHEMBL6959399 | 0.62 | HTT (0.46) | NPC1RAB9ALMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099404-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |