SCHEMBL22015230

SCHEMBL22015230

O=C(O)CC[n+]1cc(-c2ncccn2)sn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 1/20 0.36
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
TBXA2R P21731 2/20 0.33
NR4A2 P43354 1/20 0.33
HDAC1 Q13547 1/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
GAA P10253 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21963672 0.89 CYP2D6 (0.31) ALDH1A1TSHRHSD17B10CYP2D6CTNNB1
Hydrochloric Acid SCHEMBL21963932 0.86 ALDH1A1 (0.34) ALDH1A1TSHRCTNNB1WNT3ASMN1; SMN2
SCHEMBL22015232 0.86 ALDH1A1 (0.34) ALDH1A1TSHRCTNNB1WNT3ASMN1; SMN2
SCHEMBL22015234 0.84 ALDH1A1 (0.39) ALDH1A1HSD17B10SMN1; SMN2HDAC1KDM4E
SCHEMBL22014911 0.79 FDPS (0.33) ALDH1A1HDAC1
SCHEMBL22015056 0.79 LTA4H (0.37) TSHRHSD17B10CYP2D6
SCHEMBL21963931 0.78 HDAC1 (0.33) HDAC1
Bromide SCHEMBL21963675 0.78 FDPS (0.32) HDAC1
SCHEMBL21963669 0.77 PABPC1 (0.31)
SCHEMBL21963674 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099407-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-05-22 WO disclosed