Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209202 | 0.80 | HSD17B10 (0.50) | HSD17B10HRH3KCNH2DRD2HTR1A | |
| SCHEMBL17124880 | 0.77 | DRD2 (0.60) | HSD17B10HRH3KCNH2DRD2HTR1A | |
| SCHEMBL24209206 | 0.77 | HSD17B10 (0.46) | HSD17B10HRH3KCNH2DRD2HTR1A | |
| SCHEMBL18773677 | 0.73 | KMT2A (0.60) | HSD17B10HRH3KCNH2MAPTTP53 | |
| SCHEMBL24209136 | 0.73 | ALDH1A1 (0.43) | TMEM97MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL4724848 | 0.72 | MAPT (0.69) | HSD17B10HRH3KCNH2MAPTTP53 | |
| SCHEMBL27363642 | 0.72 | MAPT (0.65) | HSD17B10DRD2MAPTTP53MAPK1 | |
| SCHEMBL4720351 | 0.71 | MAPT (0.68) | HSD17B10HRH3KCNH2MAPTTP53 | |
| SCHEMBL8363117 | 0.70 | KMT2A (0.66) | HSD17B10HRH3DRD2MAPTTP53 | |
| SCHEMBL11354876 | 0.69 | HSD17B10 (1.00) | HSD17B10KCNH2DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |