Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 10/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014801 | 0.80 | HTR7 (0.43) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23701361 | 0.78 | HRH3 (0.50) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23701360 | 0.78 | HRH3 (0.50) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23701485 | 0.74 | ACACB (0.44) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23199742 | 0.74 | LMNA (0.52) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23199743 | 0.74 | LMNA (0.52) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23701487 | 0.74 | ACACB (0.44) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22015807 | 0.73 | HSD17B10 (0.52) | ALDH1A1TP53SMN1; SMN2TDP1MAPT | |
| SCHEMBL23732273 | 0.70 | CHRNB2 (0.66) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21963784 | 0.70 | CHRNB2 (0.66) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017516-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017516-A1 | LOX INHIBITORS | LOXL1, LOX, LOXL2 | ALDH1A1 122/4885TP53 2406/4885NPC1 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.