Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017240 | 0.70 | MAPK7 (0.49) | WNT3AEGFRMAPK14KIT | |
| SCHEMBL22017241 | 0.69 | KIT (0.62) | EGFRKIT | |
| SCHEMBL22018091 | 0.67 | KIT (0.61) | EGFRKIT | |
| SCHEMBL28550947 | 0.66 | WNT3A (0.33) | MEN1ALDH1A1KMT2AHPGDWNT3A | |
| SCHEMBL28546729 | 0.63 | SRC (0.33) | MEN1ALDH1A1KMT2AHPGDWNT3A | |
| SCHEMBL20033130 | 0.61 | PDE4B (0.44) | MEN1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10877787 | 0.60 | HTR1B (0.58) | HRH3MEN1ALDH1A1KMT2ADRD3 | |
| SCHEMBL22017771 | 0.59 | MAPT (0.47) | MEN1KMT2AHTR2ACYP2D6CYP2C19 | |
| SCHEMBL2949573 | 0.58 | RAD52 (0.61) | MEN1ALDH1A1KMT2ADRD3HPGD | |
| SCHEMBL14452258 | 0.57 | DRD2 (0.48) | MEN1KMT2ADRD3DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |