SCHEMBL22018210

SCHEMBL22018210

CCC(CC)n1c(=O)c2ccc3c4ccccc4sc4c(C#Cc5ccc(N)o5)cc(c1=O)c2c43

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018211 0.85 MEN1 (0.37) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL22018208 0.85 MAPT (0.32) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL22019252 0.84 KDM4E (0.32) MEN1KMT2AKDM4EALDH1A1TSHR
SCHEMBL22018386 0.83 HCRTR1 (0.36) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL22018212 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL22018224 0.82
SCHEMBL22018385 0.81 MAPT (0.31) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL22018213 0.76 KMT2A (0.36) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL22018615 0.72 ALDH1A1 (0.41) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL22018214 0.71 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099793-A1 NOVEL BENZOTHIOXANTHENE P-CONJUGATED MOLECULES FOR ENERGY STORAGE UNIVERSITE D'ANGERS (FR) 2020-05-22 WO disclosed