SCHEMBL22018615

SCHEMBL22018615

CCC(CC)n1c(=O)c2ccc3sc4ccccc4c4ccc(c1=O)c2c34

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
GPR3 P46089 1/20 0.38
MAPT P10636 6/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CASP3 P42574 1/20 0.37
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
POLB P06746 1/20 0.35
DUSP3 P51452 1/20 0.35
BLM P54132 1/20 0.35
PTPN5 P54829 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30782401 0.86 TDP1 (0.34) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL13637522 0.85 ALDH1A1 (0.44) ALDH1A1GPR3MAPTRAB9ANPC1
SCHEMBL22018213 0.82 KMT2A (0.36) ALDH1A1MAPTRAB9AHPGDCYP1A2
SCHEMBL10154408 0.82 CASP3 (0.43) ALDH1A1GPR3MAPTRAB9ANPC1
SCHEMBL11974069 0.80 GPR3 (0.45) ALDH1A1GPR3MAPTRAB9ANPC1
SCHEMBL13799551 0.77 TDP1 (0.57) ALDH1A1NPC1HPGDTDP1POLB
SCHEMBL14393100 0.77 GPR3 (0.45) ALDH1A1GPR3MAPTRAB9ANPC1
SCHEMBL10123978 0.76 GPR3 (0.41) ALDH1A1GPR3MAPTRAB9ANPC1
SCHEMBL24270357 0.76 MAPT (0.40) ALDH1A1MAPTRAB9ANPC1HPGD
SCHEMBL559250 0.75 TDP1 (0.51) ALDH1A1MAPTNPC1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099793-A1 NOVEL BENZOTHIOXANTHENE P-CONJUGATED MOLECULES FOR ENERGY STORAGE UNIVERSITE D'ANGERS (FR) 2020-05-22 WO disclosed