Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017875 | 0.86 | NPC1 (0.39) | NPC1MEN1KMT2ATP53RAB9A | |
| SCHEMBL22018050 | 0.85 | ALDH1A1 (0.47) | NPC1MEN1KMT2ARAB9AHDAC2 | |
| SCHEMBL28634617 | 0.79 | CA2 (0.41) | HTTHDAC2HDAC8HDAC6CA12 | |
| SCHEMBL22018668 | 0.78 | CA2 (0.50) | LMNAPOLBHDAC2HDAC8HDAC6 | |
| SCHEMBL22018290 | 0.77 | CA12 (0.41) | NPC1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL22018040 | 0.75 | KDM4E (0.48) | MEN1KMT2ATP53GAAPOLB | |
| SCHEMBL22018046 | 0.75 | LMNA (0.41) | NPC1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL22018670 | 0.74 | SMN1; SMN2 (0.44) | NPC1MEN1KMT2ATP53RAB9A | |
| SCHEMBL22018656 | 0.74 | KMT2A (0.42) | NPC1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL22018666 | 0.74 | CA2 (0.50) | KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329629-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |