SCHEMBL22018328

SCHEMBL22018328

CCC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 7/20 0.47
▸ NPY4R P50391 7/20 0.47
▸ NPY5R Q15761 7/20 0.47
▸ NPY1R P25929 5/20 0.47
▸ HCRTR1 O43613 1/20 0.46
▸ HCRTR2 O43614 1/20 0.46
▸ GLP1R P43220 1/20 0.45
▸ GCGR P47871 1/20 0.45
▸ GIPR P48546 1/20 0.45
▸ NTSR1 P30989 2/20 0.45
▸ F2 P00734 2/20 0.45
▸ CXCR4 P61073 1/20 0.45
▸ CALCR P30988 2/20 0.44
▸ OPRD1 P41143 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25524949 0.96 F2 (0.45) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22018499 0.96 NTSR1 (0.45) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22018329 0.95 NPY2R (0.47) NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL29308344 0.95 OPRD1 (0.43) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22018604 0.95 APLNR (0.45) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22019191 0.95 NPY2R (0.46) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22922809 0.95 NPY2R (0.46) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22018361 0.95 APLNR (0.46) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22922932 0.95 APLNR (0.46) NPY2RNPY4RNPY5RNPY1RHCRTR1
SCHEMBL22018477 0.95 APLNR (0.46) NPY2RNPY4RNPY5RNPY1RHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT YUYU PHARMA, INC. (KR) 2021-01-28 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR NPY2R 337/4885NPY4R 794/4885NPY5R 291/4885
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP NPY2R 441/4885NPY4R 503/4885NPY5R 604/4885
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT VIP, NGLY1, PROKR1 NPY2R 727/4885NPY4R 1291/4885NPY5R 592/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 NPY2R 435/4885NPY4R 762/4885NPY5R 303/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR NPY2R 337/4885NPY4R 794/4885NPY5R 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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