Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831279 | 0.81 | LMNA (0.58) | LMNAL3MBTL1PTGESALDH1A1TP53 | |
| SCHEMBL4215761 | 0.78 | LMNA (0.74) | LMNAL3MBTL1PTGESALDH1A1TP53 | |
| SCHEMBL13831736 | 0.76 | ALDH1A1 (0.80) | LMNAL3MBTL1ALDH1A1GAAMAPK1 | |
| SCHEMBL18559236 | 0.75 | LMNA (1.00) | LMNAALDH1A1NPSR1GAATHRB | |
| SCHEMBL13831637 | 0.74 | TP53 (0.55) | LMNAL3MBTL1PTGESALDH1A1TP53 | |
| SCHEMBL22018800 | 0.73 | LMNA (0.52) | LMNAL3MBTL1PTGESALDH1A1TP53 | |
| SCHEMBL13832116 | 0.73 | TP53 (0.56) | LMNAL3MBTL1PTGESALDH1A1TP53 | |
| SCHEMBL13832230 | 0.72 | NPSR1 (0.64) | LMNAALDH1A1TP53NPSR1GAA | |
| SCHEMBL15983233 | 0.71 | NPSR1 (0.76) | LMNAALDH1A1TP53NPSR1GAA | |
| SCHEMBL16493338 | 0.71 | ATM (0.68) | LMNAL3MBTL1ALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |