Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832116 | 0.83 | TP53 (0.56) | LMNAL3MBTL1PTGESALDH1A1MAPT | |
| SCHEMBL4215761 | 0.82 | LMNA (0.74) | LMNAL3MBTL1PTGESALDH1A1MAPT | |
| SCHEMBL13831736 | 0.78 | ALDH1A1 (0.80) | LMNAL3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL13831637 | 0.75 | TP53 (0.55) | LMNAL3MBTL1PTGESALDH1A1MAPT | |
| SCHEMBL4205567 | 0.73 | LMNA (0.66) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13831279 | 0.73 | LMNA (0.58) | LMNAL3MBTL1PTGESALDH1A1POLB | |
| SCHEMBL22018480 | 0.73 | LMNA (0.59) | LMNAL3MBTL1PTGESALDH1A1MAPT | |
| SCHEMBL13831457 | 0.72 | MEN1 (0.61) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL15983682 | 0.72 | ALDH1A1 (0.73) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4206993 | 0.72 | THRB (0.65) | LMNAL3MBTL1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |