Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019363 | 0.84 | ALDH1A1 (0.49) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL13832268 | 0.83 | ALDH1A1 (0.61) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22019616 | 0.79 | ALDH1A1 (0.45) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22018910 | 0.79 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22019358 | 0.77 | KMT2A (0.45) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL13832083 | 0.76 | MEN1 (0.60) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22018914 | 0.75 | LMNA (0.44) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL13832262 | 0.73 | ALDH1A1 (0.61) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22018792 | 0.71 | LMNA (0.49) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22018940 | 0.71 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |