Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019363 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2ATP53MEN1 | |
| SCHEMBL13832029 | 0.83 | NPSR1 (0.54) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15986448 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL22019615 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1TP53SMN1; SMN2LMNAKDM4E | |
| SCHEMBL22018795 | 0.79 | KMT2A (0.53) | ALDH1A1HTTKMT2ATP53MEN1 | |
| SCHEMBL22018910 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22018914 | 0.76 | LMNA (0.44) | ALDH1A1HTTKMT2ATP53MEN1 | |
| SCHEMBL22019358 | 0.74 | KMT2A (0.45) | ALDH1A1HTTKMT2ATP53MEN1 | |
| SCHEMBL15983258 | 0.72 | NPSR1 (0.60) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13832036 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KMT2ATP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |