Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445455 | 0.89 | CYP19A1 (0.50) | GAAKDM4EHSD17B10ALDH1A1TRPA1 | |
| SCHEMBL5271027 | 0.85 | KMT2A (0.46) | GAAKDM4EHSD17B10ALDH1A1TRPA1 | |
| SCHEMBL28091170 | 0.85 | IDO1 (0.51) | GAAHSD17B10ALDH1A1TRPA1KCNMA1 | |
| SCHEMBL11474259 | 0.82 | GUCY1A1 (0.54) | GAAKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL2901815 | 0.80 | PLK1 (0.46) | GAATRPA1KCNMA1TDP1 | |
| SCHEMBL30086871 | 0.80 | CYP3A4 (0.50) | GAAHSD17B10ALDH1A1TRPA1KCNMA1 | |
| SCHEMBL1259060 | 0.80 | CYP3A4 (0.50) | GAAHSD17B10ALDH1A1TRPA1KCNMA1 | |
| SCHEMBL15292156 | 0.79 | KDM4E (0.44) | GAAKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL18647897 | 0.79 | KDM4E (0.44) | GAAKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL3875798 | 0.78 | KMT2A (0.60) | GAAKDM4EHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496849-B2 | COMPOSITION FOR THE OXIDATION DYEING OF HUMAN KERATINOUS FIBRES | OREAL (FR) | 2019-03-27 | — | — | EP | disclosed |
| US-9402797-B2 | Multi-tonal one step dyes III | HENKEL AG & CO. KGAA (DE) | 2016-08-02 | — | — | US | disclosed |
| US-20150374602-A1 | MULTI-TONAL ONE STEP DYES III | HENKEL AG & CO. KGAA (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | US | disclosed |
| US-7476261-B2 | vivid color to hair without causing decomposition of the direct azo dye; excellent fastness to light, wash, sweat, friction and heat; stable to alkalizing agents and oxidizing agents; 4-azo-2,1,3-BENZOTHIADIAZOLE dyes | KAO CORPORATION (JP) | 2009-01-13 | — | — | US | disclosed |
| US-20080134448-A1 | Hair Dye Composition | KAO CORPORATION (JP) | 2008-06-12 | — | — | US | disclosed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| EP-1377974-A1 | OPTICAL DATA CARRIER CONTAINING A XANTHENE DYE IN THE INFORMATION LAYER THEREOF AS A LIGHT-ABSORBING COMPOUND | Bayer Chemicals AG (DE) | 2004-01-07 | — | — | EP | disclosed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
| WO-2002077984-A1 | OPTICAL DATA CARRIER CONTAINING A XANTHENE DYE IN THE INFORMATION LAYER THEREOF AS A LIGHT-ABSORBING COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | GAA 4684/4885KDM4E 1476/4885HSD17B10 1556/4885 |
| US-20110162671-A1 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | KRT18, CBR3, ACOX3 | GAA 1991/4885KDM4E 2152/4885HSD17B10 427/4885 |
| US-20080134448-A1 | Hair Dye Composition | MC1R, CYB5R3, MC5R | GAA 4840/4885KDM4E 1418/4885HSD17B10 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.