Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018972 | 0.85 | KMT2A (0.50) | MAPTHPGDHDAC6ALDH1A1POLB | |
| SCHEMBL15983268 | 0.80 | HPGD (0.69) | MAPTHPGDPTK2ALDH1A1POLB | |
| SCHEMBL21123650 | 0.78 | TP53 (0.78) | MAPTHPGDHDAC2PTK2HDAC3 | |
| SCHEMBL6406110 | 0.78 | HPGD (0.73) | MAPTHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL18558946 | 0.74 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL15983427 | 0.74 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL6402672 | 0.74 | DGAT1 (0.57) | MAPTHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL6406153 | 0.73 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL6209335 | 0.72 | LMNA (0.77) | MAPTHDAC2PTK2HDAC3HDAC1 | |
| SCHEMBL6274942 | 0.72 | MAPT (0.47) | MAPTHPGDHDAC2PTK2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |