Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018952 | 0.85 | MAPT (0.60) | POLBSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL22047016 | 0.83 | KMT2A (0.47) | KMT2AMEN1POLBSMN1; SMN2HPGD | |
| SCHEMBL15983340 | 0.81 | HPGD (0.61) | KMT2APOLBSMN1; SMN2HPGDLMNA | |
| SCHEMBL22018967 | 0.80 | ALDH1A1 (0.51) | KMT2AMEN1POLBSMN1; SMN2HPGD | |
| SCHEMBL22018979 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1POLBSMN1; SMN2LMNA | |
| SCHEMBL22018968 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1POLBSMN1; SMN2HPGD | |
| SCHEMBL15983331 | 0.72 | TP53 (0.45) | KMT2AMEN1POLBHPGDMAPT | |
| SCHEMBL13831858 | 0.71 | DGAT1 (0.45) | KMT2APOLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6406110 | 0.70 | HPGD (0.73) | KMT2AMEN1POLBHPGDLMNA | |
| SCHEMBL13831816 | 0.70 | MEN1 (0.50) | KMT2AMEN1POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |