Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300758 | 0.83 | RAPGEF4 (0.50) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL11474256 | 0.79 | GAA (0.48) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL24893149 | 0.76 | RAB9A (0.41) | GAAALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL11693372 | 0.76 | ALDH1A1 (0.47) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL10990546 | 0.75 | RAPGEF4 (0.43) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL22643737 | 0.74 | MAPT (0.46) | GAAALDH1A1HTTKDM4EKMT2A | |
| SCHEMBL24595009 | 0.73 | RAPGEF4 (0.42) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL28264872 | 0.73 | RAPGEF4 (0.54) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL12451042 | 0.73 | GAA (0.55) | RAPGEF4GAAALDH1A1HTTKDM4E | |
| SCHEMBL27315444 | 0.73 | RAPGEF4 (0.54) | RAPGEF4GAAALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |