Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362209 | 0.84 | RAB9A (0.44) | RAB9ACRHR1GAAHTTMEN1 | |
| SCHEMBL22019079 | 0.76 | RAPGEF4 (0.47) | RAB9AGAAHTTMEN1LMNA | |
| SCHEMBL22019354 | 0.73 | NOX1 (0.47) | RAB9AGAAHTTMEN1LMNA | |
| SCHEMBL8047103 | 0.73 | KCNH2 (0.39) | RAB9ACRHR1LMNAMAPTKMT2A | |
| SCHEMBL11193851 | 0.73 | RAB9A (0.46) | RAB9ACRHR1GAAHTTMEN1 | |
| SCHEMBL11056044 | 0.73 | RAB9A (0.46) | RAB9ACRHR1GAAHTTMEN1 | |
| SCHEMBL11056480 | 0.73 | RAB9A (0.46) | RAB9ACRHR1GAAHTTMEN1 | |
| SCHEMBL5768693 | 0.73 | RAB9A (0.47) | RAB9AGAAHTTMEN1LMNA | |
| SCHEMBL2137896 | 0.71 | CA1 (0.50) | RAB9AGAAHTTMEN1LMNA | |
| SCHEMBL11404110 | 0.71 | RAB9A (0.50) | RAB9AGAAHTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119141-A1 | NELOTANSERIN FOR THE PROPHYLAXIS AND TREATMENT OF REM SLEEP BEHAVIOR DISORDER | Axovant Sciences GmbH (CH) | 2023-01-18 | — | — | EP | disclosed |