Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 4/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962546 | 1.00 | VNN1 (0.42) | VNN1TRPV1KMT2ARBP4MLYCD | |
| SCHEMBL22020044 | 0.91 | VNN1 (0.43) | VNN1KMT2AMLYCDCNR2CCR2 | |
| SCHEMBL21962852 | 0.91 | VNN1 (0.43) | VNN1KMT2AMLYCDCNR2CCR2 | |
| SCHEMBL21962600 | 0.83 | HPGD (0.42) | VNN1TRPV1KMT2ARBP4SRD5A2 | |
| SCHEMBL21962542 | 0.80 | RAF1 (0.48) | VNN1MLYCDSCDHPGDKDM4E | |
| SCHEMBL21962451 | 0.80 | MEN1 (0.41) | VNN1KMT2ARBP4SRD5A2CNR2 | |
| SCHEMBL21962674 | 0.79 | SCD (0.47) | VNN1MLYCDSCDHPGDKDM4E | |
| SCHEMBL22020041 | 0.79 | ALDH1A1 (0.47) | VNN1KMT2AMLYCDSRD5A2SCD | |
| SCHEMBL21962779 | 0.79 | MLYCD (0.49) | KMT2AMLYCDSRD5A2SCDHPGD | |
| SCHEMBL21962568 | 0.79 | LMNA (0.51) | KMT2AMLYCDSRD5A2SCDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |