SCHEMBL22019265

SCHEMBL22019265

CP(C)(=O)c1cccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccc(P(C)(C)=O)c5)cc4)c4ccccc34)cc2)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 5/20 0.36
GRIK1 P39086 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
ACHE P22303 4/20 0.34
GGPS1 O95749 1/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
PTPN1 P18031 1/20 0.33
FEN1 P39748 1/20 0.33
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
SMO Q99835 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
FDPS P14324 1/20 0.32
MMP8 P22894 1/20 0.32
MMP14 P50281 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18893042 0.98 HDAC8 (0.38) PTPN5GRIK1HDAC8ACHEGGPS1
SCHEMBL18893073 0.95 ACHE (0.37) PTPN5HDAC8ACHEGGPS1PTPN1
SCHEMBL22019488 0.95 ACHE (0.35) PTPN5GRIK1ACHE
SCHEMBL23129228 0.94 FEN1 (0.35) PTPN5GRIK1HDAC8ACHEGGPS1
SCHEMBL23129227 0.92 ACHE (0.35) PTPN5GRIK1HDAC8ACHEGGPS1
SCHEMBL19002149 0.92 ACHE (0.37) PTPN5GRIK1HDAC8ACHEGGPS1
SCHEMBL30980792 0.92 ACHE (0.37) PTPN5GRIK1HDAC8ACHEGGPS1
SCHEMBL22019274 0.91 ESR1 (0.34) GRIK1HDAC8ACHECA2
SCHEMBL18893071 0.91 ALOX5 (0.41) CA2CA9CA12CA1
SCHEMBL22019686 0.90 CYP1A2 (0.35) PTPN5GRIK1HDAC8ACHEGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194442-A1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2023-06-14 EP disclosed
EP-3406599-B1 ORGANIC ELECTRONIC DEVICE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER NOVALED GMBH (DE) 2023-02-22 EP disclosed
US-20200161559-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200161559-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer C1S, YAP1, ESR1 PTPN5 2894/4885GRIK1 1679/4885HDAC8 4010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.