Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | RPA1 | P27694 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893073 | 0.97 | ACHE (0.37) | ACHEESR1ESR2PTPN5 | |
| SCHEMBL22019274 | 0.96 | ESR1 (0.34) | ACHEGRIK1ALOX5ESR1ESR2 | |
| SCHEMBL22019265 | 0.95 | PTPN5 (0.36) | ACHEGRIK1PTPN5 | |
| SCHEMBL22020406 | 0.95 | ESR1 (0.33) | ACHEGRIK1ALOX5ESR1 | |
| SCHEMBL30980792 | 0.93 | ACHE (0.37) | ACHEGRIK1ESR1ESR2DPP4 | |
| SCHEMBL18893042 | 0.93 | HDAC8 (0.38) | ACHEGRIK1ESR1PTPN5 | |
| SCHEMBL19002149 | 0.93 | ACHE (0.37) | ACHEGRIK1ESR1ESR2DPP4 | |
| SCHEMBL22020842 | 0.92 | HDAC8 (0.34) | ACHEGRIK1MCL1 | |
| SCHEMBL23129227 | 0.90 | ACHE (0.35) | ACHEGRIK1ESR1ESR2DPP4 | |
| SCHEMBL21881902 | 0.89 | L3MBTL1 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200161559-A1 | Organic Electronic Device Comprising an Organic Semiconductor Layer | NOVALED GMBH (DE) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200161559-A1 | Organic Electronic Device Comprising an Organic Semiconductor Layer | C1S, YAP1, ESR1 | ACHE 1502/4885GRIK1 1679/4885ALOX5 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.