Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019405 | 0.82 | LRRK2 (0.58) | LRRK2CYP3A4CYP2C19LMNACPB1 | |
| SCHEMBL22019389 | 0.82 | ALDH1A1 (0.58) | LRRK2CYP3A4CYP2C19LMNAALDH1A1 | |
| SCHEMBL22019397 | 0.81 | KDM4E (0.63) | LRRK2CYP3A4CYP2C19LMNACPB1 | |
| SCHEMBL15983296 | 0.80 | POLB (0.48) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL22018979 | 0.79 | ALDH1A1 (0.46) | LRRK2CYP3A4CYP2C19LMNAALDH1A1 | |
| SCHEMBL22019393 | 0.79 | LRRK2 (0.54) | LRRK2CYP3A4CYP2C19LMNACPB1 | |
| SCHEMBL22019401 | 0.79 | CPB1 (0.68) | LRRK2CYP3A4CYP2C19LMNACPB1 | |
| SCHEMBL22018586 | 0.74 | ALDH1A1 (0.46) | LRRK2CYP3A4CYP2C19LMNAALDH1A1 | |
| SCHEMBL1543876 | 0.73 | KDM4E (0.60) | CYP3A4ALDH1A1KDM4ESMN1; SMN2MIF | |
| SCHEMBL13830844 | 0.69 | KDM4E (0.48) | CYP3A4CYP2C19CPB1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |