Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 3/20 | 0.30 |
| ▸ | GCKR | Q14397 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962132 | 0.85 | CA2 (0.47) | L3MBTL1CA2 | |
| SCHEMBL21962134 | 0.85 | CA2 (0.47) | L3MBTL1CA2 | |
| SCHEMBL21962541 | 0.85 | CA2 (0.47) | L3MBTL1CA2 | |
| SCHEMBL18371496 | 0.77 | L3MBTL1 (0.45) | LOXL3MBTL1LOXL2LMNATSHR | |
| SCHEMBL28132164 | 0.72 | DAO (0.42) | LOXL3MBTL1LOXL2CA2 | |
| SCHEMBL22020343 | 0.72 | KDM4E (0.36) | L3MBTL1LMNATSHR | |
| SCHEMBL22020730 | 0.70 | FFAR2 (0.36) | LOXLOXL2GCKGCKR | |
| SCHEMBL19436416 | 0.70 | LOX (0.57) | LOXL3MBTL1LOXL2CA2LMNA | |
| SCHEMBL1838092 | 0.68 | LOX (0.58) | LOXLOXL2 | |
| SCHEMBL7144005 | 0.66 | CA2 (0.44) | L3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20160248025-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-08-25 | — | — | US | disclosed |