Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131987 | 0.86 | LTA4H (0.53) | PPARAPPARGPPARDALOX5LTA4H | |
| SCHEMBL21074676 | 0.83 | HMGCR (0.52) | PPARAPPARGPPARDLTA4HMAOB | |
| SCHEMBL5936806 | 0.83 | MAOB (0.52) | MAOBLMNALPAR1LPAR3 | |
| SCHEMBL12894592 | 0.83 | LMNA (0.58) | PPARAPPARGPPARDALOX5LTA4H | |
| SCHEMBL19668693 | 0.80 | PPARG (0.57) | PPARAPPARGPPARDLTA4HMAOB | |
| SCHEMBL12876205 | 0.79 | POLB (0.50) | LMNA | |
| SCHEMBL8011004 | 0.78 | ALOX5 (0.51) | ALOX5LTA4HMAOBLMNAL3MBTL1 | |
| SCHEMBL5295621 | 0.78 | LMNA (0.52) | PPARAPPARGPPARDALOX5LTA4H | |
| SCHEMBL5664710 | 0.77 | HMGCR (0.57) | EPHX2 | |
| SCHEMBL20582562 | 0.77 | LMNA (0.50) | ALOX5LTA4HMAOBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660884-B2 | Phosphonate-chloroquine conjugates and methods using same | UNIVERSITY OF ROCHESTER (US) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660884-B2 | Phosphonate-chloroquine conjugates and methods using same | PHPT1, ENPP2, QPCT | PPARA 1494/4885PPARG 1824/4885PPARD 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.