Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262405 | 0.90 | ACHE (0.36) | ACHELMNARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL6071498 | 0.82 | ACHE (0.36) | ACHELMNARECQLSMN1; SMN2 | |
| SCHEMBL12877389 | 0.81 | SCD (0.40) | ACHELMNARECQLALDH1A1ESRRA | |
| SCHEMBL12379165 | 0.81 | ACHE (0.39) | ACHELMNARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL24958399 | 0.78 | ACHE (0.36) | ACHELMNARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL14262390 | 0.78 | CA12 (0.44) | LMNARECQL | |
| SCHEMBL25617485 | 0.78 | GPR88 (0.34) | ACHELMNARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL21908208 | 0.78 | LMNA (0.40) | LMNARECQLALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL18767837 | 0.78 | ACHE (0.39) | ACHELMNARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL15158980 | 0.76 | LMNA (0.33) | LMNARECQLALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | NAMPT, NNT, NNMT | ACHE 4629/4885LMNA 1042/4885RECQL 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.