SCHEMBL22026757

SCHEMBL22026757

CC(C)NC(=O)C(CCCNC(=O)O)NC(=O)C(N)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 3/20 0.40
▸ DPP4 P27487 2/20 0.40
▸ DPP8 Q6V1X1 2/20 0.40
▸ DPP9 Q86TI2 2/20 0.40
▸ FAP Q12884 1/20 0.38
▸ SIRT5 Q9NXA8 2/20 0.37
▸ NMT2 O60551 1/20 0.35
▸ NMT1 P30419 1/20 0.35
▸ SIRT6 Q8N6T7 1/20 0.35
▸ SIRT1 Q96EB6 1/20 0.35
▸ NPY4R P50391 6/20 0.34
▸ NPY1R P25929 4/20 0.34
▸ NPY2R P49146 2/20 0.34
▸ NPY5R Q15761 2/20 0.34
▸ KISS1R Q969F8 1/20 0.34
▸ EPHX1 P07099 1/20 0.33
▸ FURIN P09958 1/20 0.33
▸ NOD1 Q9Y239 1/20 0.33
▸ GNPAT O15228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22026756 1.00 DPP7 (0.40) DPP7DPP4DPP8DPP9FAP
SCHEMBL21323139 0.89 DPP4 (0.40) DPP7DPP4DPP8DPP9FAP
SCHEMBL22026752 0.85 EPHX1 (0.39) SIRT5NMT2NMT1SIRT6SIRT1
SCHEMBL22026768 0.80 SIRT1 (0.41) DPP7SIRT5NMT2NMT1SIRT6
SCHEMBL30302920 0.80 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL21137521 0.79 DPP4 (0.40) DPP7DPP4DPP8DPP9FAP
SCHEMBL22026827 0.79 DPP7 (0.49) DPP7DPP4DPP8DPP9EPHX1
SCHEMBL16862522 0.78 C3AR1 (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL6047671 0.78 C3AR1 (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL28819908 0.78 C3AR1 (0.46) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692008-B2 Preparation and uses of reactive oxygen species scavenger derivatives XWPharma Ltd. (KY) 2023-07-04 — — US disclosed
EP-3668837-B1 PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES XWPHARMA LTD (KY) 2022-07-06 — — EP disclosed
US-20210047367-A1 PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES XWPharma Ltd. (KY) 2021-02-18 — — US disclosed
US-10858394-B2 Preparation and uses of reactive oxygen species scavenger derivatives XW LABORATORIES INC. (KY) 2020-12-08 — — US disclosed
US-20200181194-A1 PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES XWPharma Ltd. (KY) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181194-A1 PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES AIFM2, GPX1, GPX4 DPP7 4560/4885DPP4 4473/4885DPP8 4543/4885
US-20210047367-A1 PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES AIFM2, GPX1, GPX4 DPP7 4560/4885DPP4 4473/4885DPP8 4543/4885
US-11692008-B2 Preparation and uses of reactive oxygen species scavenger derivatives AIFM2, GPX1, GPX4 DPP7 4560/4885DPP4 4473/4885DPP8 4543/4885
US-10858394-B2 Preparation and uses of reactive oxygen species scavenger derivatives AIFM2, GPX1, GPX4 DPP7 4560/4885DPP4 4473/4885DPP8 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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