SCHEMBL22028071

SCHEMBL22028071

CC(C)=NO.CC(C)=NO.CC(C)=NO.C[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202872 1.00 ALDH1A1 (0.38) ALDH1A1THRBBLMPMP22NPSR1
SCHEMBL28296161 1.00
SCHEMBL8054304 0.89
SCHEMBL2206 0.89
SCHEMBL8525707 0.84
Water SCHEMBL5438890 0.84
SCHEMBL9078915 0.84
Hydrochloric Acid SCHEMBL6541913 0.84
SCHEMBL30146908 0.84
SCHEMBL28235050 0.84 ALDH1A1 (0.40) ALDH1A1THRBBLMPMP22NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834556-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-20220220260-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-14 US disclosed
US-11319413-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-03 US disclosed
US-20210206924-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-07-08 US disclosed
EP-3705535-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2020-09-09 EP disclosed
US-20200181911-A1 SILICONE MEMBRANES HOLCIM TECHNOLOGY LTD (CH) 2020-06-11 US disclosed
CN-105112007-A Single-component organosilicon sealant for LED (light-emitting diode) packaging and preparation method thereof BLUESTAR CHENGDU NEW MATERIAL CO LTD 2015-12-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220260-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SEM1, ILK, SI ALDH1A1 1281/4885THRB 2676/4885BLM 181/4885
US-20210206924-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SEM1, ILK, SI ALDH1A1 1281/4885THRB 2676/4885BLM 181/4885
US-11834556-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SEM1, ILK, SI ALDH1A1 1281/4885THRB 2676/4885BLM 181/4885
US-11319413-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SEM1, ILK, SI ALDH1A1 1281/4885THRB 2676/4885BLM 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.