Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029370 | 0.89 | TDP1 (0.41) | TDP1POLBALDH1A1FABP1PLAAT3 | |
| SCHEMBL31682037 | 0.88 | PKM (0.39) | TDP1POLBALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL22029365 | 0.87 | ALDH1A1 (0.38) | TDP1POLBALDH1A1HDAC1TBXA2R | |
| SCHEMBL22029391 | 0.85 | CA12 (0.48) | ALDH1A1FABP1HDAC1HDAC8 | |
| SCHEMBL31682053 | 0.84 | HDAC1 (0.44) | TDP1POLBALDH1A1FABP1HDAC1 | |
| SCHEMBL31682055 | 0.84 | HDAC1 (0.44) | TDP1POLBALDH1A1FABP1HDAC1 | |
| SCHEMBL31681994 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HDAC1TBXA2RTBXAS1NAMPT | |
| SCHEMBL31682054 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HDAC1TBXA2RTBXAS1NAMPT | |
| SCHEMBL31682105 | 0.83 | PKM (0.40) | TDP1POLBALDH1A1FABP1HDAC1 | |
| SCHEMBL31681968 | 0.82 | POLB (0.50) | TDP1POLBHDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893934-B1 | INSULIN CONJUGATES | SANOFI SA (FR) | 2025-09-10 | — | — | EP | disclosed |
| US-12195510-B2 | Insulin conjugates | SANOFI (FR) | 2025-01-14 | — | — | US | disclosed |
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885POLB 4107/4885ALDH1A1 1829/4885 |
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885POLB 4107/4885ALDH1A1 1829/4885 |
| US-12195510-B2 | Insulin conjugates | IAPP, INSR, IGF1R | TDP1 4783/4885POLB 4107/4885ALDH1A1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.