Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029433 | 0.94 | HDAC8 (0.34) | HDAC8GPBAR1HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL21707891 | 0.92 | HDAC8 (0.36) | HDAC8RXFP1GPBAR1HSD11B1SLC6A2 | |
| SCHEMBL30979910 | 0.92 | HDAC8 (0.36) | HDAC8RXFP1GPBAR1HSD11B1SLC6A2 | |
| SCHEMBL21701238 | 0.90 | RXFP1 (0.37) | HDAC8RXFP1GPBAR1HSD11B1SLC6A2 | |
| SCHEMBL30979920 | 0.89 | HDAC8 (0.35) | HDAC8GPBAR1HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL21707893 | 0.89 | HDAC8 (0.35) | HDAC8GPBAR1HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL24626045 | 0.89 | GPBAR1 (0.34) | HDAC8GPBAR1SLC6A2SLC6A4S1PR1 | |
| SCHEMBL29857385 | 0.88 | RXFP1 (0.40) | HDAC8RXFP1GPBAR1HSD11B1SLC6A2 | |
| SCHEMBL23251050 | 0.88 | RXFP1 (0.40) | HDAC8RXFP1GPBAR1HSD11B1SLC6A2 | |
| SCHEMBL23053046 | 0.88 | P2RX7 (0.37) | HDAC8GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816150-B1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC SHANGHAI INT TRADING CO LTD (CN) | 2024-07-24 | — | — | EP | claimed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | claimed |
| EP-3816150-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Cac Shanghai International Trading Co., Ltd. (CN) | 2021-05-05 | — | — | EP | claimed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | claimed |
| EP-3816150-B1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC SHANGHAI INT TRADING CO LTD (CN) | 2024-07-24 | — | — | EP | disclosed |
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| EP-3816150-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Cac Shanghai International Trading Co., Ltd. (CN) | 2021-05-05 | — | — | EP | disclosed |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | CAC SHANGHAI INTERNATIONAL TRADING CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11540516-B2 | M-diamide compound and preparation method therefor and use thereof | DIMT1, DDT, MRM1 | HDAC8 1693/4885RXFP1 581/4885GPBAR1 3748/4885 |
| US-20200178525-A1 | M-DIAMIDE COMPOUND AND PREPARATION METHOD THEREOF AND USE THEREOF | DDT, DIMT1, QDPR | HDAC8 1546/4885RXFP1 1166/4885GPBAR1 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.