Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205924 | 0.92 | MEN1 (0.53) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL2208675 | 0.87 | LTA4H (0.56) | LTA4HCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1586484 | 0.85 | CYP3A4 (0.66) | LTA4HTSHRMEN1CYP1A2POLB | |
| SCHEMBL1585862 | 0.85 | CYP3A4 (0.66) | LTA4HTSHRMEN1CYP1A2POLB | |
| SCHEMBL3339105 | 0.85 | CYP3A4 (0.66) | LTA4HTSHRMEN1CYP1A2POLB | |
| SCHEMBL3337731 | 0.85 | CYP3A4 (0.66) | LTA4HTSHRMEN1CYP1A2POLB | |
| SCHEMBL3355647 | 0.85 | CYP3A4 (0.54) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL2210228 | 0.84 | LTA4H (0.53) | LTA4HTSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL3121215 | 0.83 | DRD2 (0.54) | TSHRMEN1CYP1A2POLBCYP3A4 | |
| SCHEMBL28548880 | 0.81 | MEN1 (0.52) | LTA4HTSHRMEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981460-B2 | Substituted benzyl ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | MEP1B, EBP, MEP1A | LTA4H 364/4885TSHR 3982/4885MEN1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.